1/26/2024 0 Comments Spore humanFollowing consumption of DE111 all participants showed both DE111 spores and DE111 vegetative cells present in their ileostomy bags. The contents of their ileal bags were collected every hour following consumption for eight hours, and the spore and vegetative DE111 cell counts were investigated. In the study, participants (aged 24 to 75) with ileal bags consumed 5 billion CFU of DE111 or placebo with a standardized meal each participant first took placebo, had a one-week washout period then took DE111. With access to the contents of the ileal bags, investigators were able to directly examine spore germination under real-time in-vivo conditions in the human small intestine for the first time. An ileostomy involves the disconnection of the small intestine from the colon, and reconnection to an external ileal bag. The randomized, crossover, double-blind, placebo-controlled study investigated germination activity of Deerland’s Bacillus subtilis DE111® in 11 individuals with stable ileostomies, which was IRB-approved. The study, entitled Presence and germination of the probiotic Bacillus subtilis DE111® in the human small intestinal tract, has been published in Frontiers in Microbiology. Spore-Forming Probiotic DE111® Shown to Germinate in the Human GI Tractĭeerland Probiotics & Enzymes has announced the publication of a new study that is the first of its kind to directly investigate the germination of a spore-forming probiotic strain in the human small intestines.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |